Correction: Determination of metal ion content of beverages and estimation of target hazard quotients: a comparative study

This is a correction to the following paper: Hague T, Petroczi A, Andrews PR, Barker J, Naughton DP: Determination of metal ion content of beverages and estimation of target hazard quotients: a comparative study. Chem Central J 2008, 2:13. Correction During preparation of a subsequent paper, we observed a computational error in the Target Hazard Quotients (THQ) listed in this work which have been inadvertently overestimated [1]. The overall results and conclusion of our paper with the corrected figures have remained valid. Corrections for Figures three, four and five; and Additional file three are given below in tabular form. The correct values with EFr = 365 days, EDtot-male = 63.9 years and EDtot-female = 66.7 years; BWmale = 83.11 kg, BWfemale = 69.81 kg, AT = 6 years and 30 years (non-carcinogenic) are shown in Tables 3 and 4. In keeping with the conclusion published, THQ values of apple juice and stout have remained below 1 (Tables 1 and 2), whereas the combined THQ values for red wine (both intact and ultrafiltered) have exceeded the cutoff value of 1, mainly owing to high V values (Tables 3 and 4). Although in keeping with the literature, THQ values were calculated for AT = 30 years, given the effect metals are assumed to have on health and delayed onset, AT is likely to be below 30 years. As noted in the paper, the THQ values calculated are concerning in that they are mainly above the safe level of THQ ≤ 1, which premise holds for the wine with the adjusted THQ values. It must be emphasized that the THQ value is to be judged as either below or above 1, where any value above 1 is a cause for health concern. It is notable that i) choices in value input into averaging time (AT), ii) uncertainty factor regarding the oral reference dose (RfD) and iii) bioavailability can have signifi* Correspondence: [email protected] School of Life Sciences, Kingston University, Kingston upon Thames, Surrey KT1 2EE, UK Table 1 Corrected THQ values for apple juice and stout (AT = 6 years) Metal THQ apple juice (male) THQ apple juice (female) THQ stout (male) THQ Stout (female) V 0.0092 0.0114 0.0365 0.0434 Cr * 0.0046 0.0057 0.0039 0.0046 Mn * 0.0690 0.0858 0.0278 0.0331 Ni 0.0103 0.0128 0.0006 0.0007 Cu 0.0313 0.0389 0.0089 0.0106 Zn 0.0111 0.0138 0.0025 0.0030 Pb 0.0000 0.0000 0.0000 0.0000 Σ 0.1355 0.1684 0.0802 0.0955 * above working range Hague et al. Chemistry Central Journal 2010, 4:2 http://journal.chemistrycentral.com/content/4/1/2